Changes in personality are most likely associated with tumors of which brain region?

Changes in personality are primarily linked to tumors in the frontal lobe due to the region's critical role in higher cognitive functions, emotional regulation, and social behavior. The frontal lobe is responsible for decision-making, planning, impulse control, and moderating social interactions. Tumors in this area can disrupt normal functioning, leading to behaviors that are out of character, impulsivity, changes in social behavior, and other personality alterations.

In contrast, tumors in the temporal lobe are more likely to produce memory issues or affect auditory perception and language comprehension, while those in the occipital lobe primarily affect visual processing. Tumors in the parietal lobe can influence spatial awareness and sensory integration but do not typically lead to personality changes. Thus, the frontal lobe is distinctly associated with alterations in personality when affected by a tumor.