What is a characteristic feature of Sturge-Weber syndrome?

Sturge-Weber syndrome is primarily characterized by neurocutaneous involvement, particularly in the form of a facial capillary malformation (port-wine stain) and associated neurological abnormalities. This condition is part of a group of syndromes that present with both neurological and cutaneous manifestations. Individuals with Sturge-Weber syndrome often exhibit neurological symptoms linked to the presence of an angioma or vascular malformation in the brain, which is coupled with the facial features that are seen on the skin.

The neurocutaneous features can contribute to seizures, developmental delays, and other cognitive impairments due to the cortical dysplasia associated with the condition. While conditions like cherry red spots may be associated with other medical syndromes, they are not a characteristic of Sturge-Weber syndrome specifically. Similarly, basal nuclei degeneration and involvement of the eighth cranial nerve do not characterize this syndrome and are more relevant to other neurological disorders. The defining aspect of Sturge-Weber is thus the unique combination of neurocutaneous manifestations that impact both the skin and the nervous system.