Which of the following can cause peripheral neuropathy?

Peripheral neuropathy can arise from a variety of causes, and one of the most significant groups includes diabetes and autoimmune diseases. Diabetes is particularly well-known as a leading cause of peripheral neuropathy, as high blood sugar levels can damage the small blood vessels that supply nerves, leading to nerve damage and symptoms such as pain, tingling, or loss of sensation. Autoimmune diseases, such as lupus or rheumatoid arthritis, can lead to peripheral neuropathy as the immune system may mistakenly attack the peripheral nerves, resulting in inflammation and nerve damage.

While infections, toxins, and structural abnormalities can also lead to peripheral neuropathy, they are not as universally recognized or prevalent as the aforementioned causes of diabetes and autoimmune disorders. Therefore, focusing on diabetes and autoimmune conditions provides a clearer understanding of common and impactful risk factors for peripheral neuropathy.